Positive patch test reaction to Lonicera japonica extract in a patient sensitized to formaldehyde.

A 40-year-old female patient presented with generalized eczema resistant to oral and topical steroids. The dermatitis had started on her legs after use of postepilation soothing remedies, and had become worse following liberal applications of a body lotion for ‘sensitive/allergic skin’. After remission, obtained by a short course of cyclosporin A and withdrawal from topical products, the patient was patch tested with the Societá Italiana di Dermatologia Allergologica Professionale ed Ambientale (SIDAPA) Baseline series, a cosmetic series, and her own products. She reacted positively to formaldehyde (+ at D2 and ++ at D3), fragrance mix I (+ at both D2 and D4), nickel sulfate (+ at D2 and D3),